Lp-PLA2 Rapid Quantitative Test(Chemiluminescence Immunoassay) is used for in vitro quantitative detection of the lipoprotein-associated phospholipase A2 (Lp-PLA2) concentration in human serum, plasma that contains heparin /EDTA and other anticoagulants and venous whole blood samples, mainly used for auxiliary diagnosis of cardiac diseases.
Application
Inflammation plays a crucial role in the development and instability of atherosclerotic plaques, a process known as atherogenesis. As a result, inflammatory markers have been evaluated for their association with atherosclerotic vascular disease and their potential to improve cardiovascular disease (CVD) risk stratification.
One such marker is lipoprotein-associated phospholipase A2 (Lp-PLA2), a vascular-specific inflammatory enzyme that has been shown to increase the risk of CVD events and stroke by approximately twofold. Lp-PLA2 may represent an important target for lipid-lowering therapy, as reducing its levels could potentially diminish the inflammatory nature of atherosclerosis and plaque vulnerability.
However, it remains unknown whether directly lowering inflammatory markers such as Lp-PLA2 will have a direct, beneficial impact on CVD events and mortality. Further research is needed to determine the clinical significance of targeting inflammatory pathways in the management of cardiovascular disease.
Product Specification
Sample Volume |
WB: 20μL; Serum/Plasma: 10μL |
Test Time |
10 mins |
Measuring Range |
5-1000 ng/mL |
Pack |
20T、40T、100T |
Storage |
2~30℃ |
Features
Smart - Photosensitive and Luminescent Microspheres
Rapid - Whole Blood Sample Type Supported & No Centrifuge Needed
Convenient - Room Temperature Storage & Minimal sample consumption
Clinical significance
1. Cardiovascular Risk Assessment
2. Identification of Vulnerable Plaques
3. Inflammatory Assessment in Coronary Artery Disease
4. Risk Stratification in Stroke
5. Monitoring Anti-Inflammatory Therapies
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