h-FABP Rapid Quantitative Test (Chemiluminescence Immunoassay)

Application

Cardiac fatty acid binding protein (H-FABP) is a small cytoplasmic protein with a molecular weight of 15 kDa. It is one of the most abundant proteins found in the heart and is present in various free forms within the cytoplasm of cardiac myocytes, where it is involved in the intracellular transport of long-chain fatty acids.

Cardiomyocytes are particularly sensitive to ischemia and hypoxia. When there is an early coronary artery occlusion, a rapid increase in intracellular H-FABP levels typically follows. Given the large amounts of H-FABP present in the myocardial cytoplasm, it begins to be released within an hour of myocardial injury, making it potentially valuable for the early diagnosis of high-risk patients presenting with chest pain. In fact, H-FABP is often recommended as the first choice for the diagnosis or exclusion of acute myocardial infarction within 3 hours of the onset of chest pain, due to its high specificity and sensitivity as a marker of myocardial injury.

Product Specification

Features

Smart - Photosensitive and Luminescent Microspheres

Rapid - Whole Blood Sample Type Supported & No Centrifuge Needed

Convenient - Room Temperature Storage & Minimal sample consumption

Clinical significance

1. Evaluation of Unstable Angina and Ischemic Events

2. Assessment of Cardiac Ischemia in Non-cardiac Surgery

3. Prognostic Marker in Heart Failure

4. Rule-Out of Acute Coronary Syndromes (ACS)

5. Detection of Acute Myocardial Infarction (AMI)