Ferritin Rapid Quantitative Test (Chemiluminescence Immunoassay)

Application

Ferritin is a soluble tissue protein that stores iron in the human body. It is the most iron-rich protein complex, with a molecular weight of about 450,000 and containing 17% to 23% iron. Ferritin exists in various tissues and cells, especially in the liver, spleen, bone marrow, brain, and peripheral blood cells, including red blood cells, white blood cells, and platelets. Normal human serum contains a small amount of ferritin.

Ferritin plays an important dual role in the human body. It serves as a "reservoir" of iron for hemoglobin synthesis, and it also acts as a hollowed-in spherical protein that protects cells from excessive amounts of free iron, which can cause harmful effects.

Certain conditions can lead to increased ferritin levels in the body:

1. Acute infections and inflammatory diseases can promote the production of ferritin, the natural iron storage protein.

2. Hyperthyroidism can also cause ferritin to rise.

3. The increase of ferritin in malignant tumors is due to tumor invasion and necrosis, as well as the reduced ability of the liver to clear ferritin, and the increased synthesis of ferritin in tumor cells.

Specific types of cancer that can increase ferritin levels include:

Acute non-lymphocytic leukemia

Lymphoma

Liver cancer

Pancreatic cancer

Lung cancer

However, esophageal cancer, stomach cancer, colon cancer, and urinary system malignancies do not significantly affect ferritin levels.

Serum ferritin measurement can be used as a therapeutic indicator. Serum ferritin levels decrease in patients with effective treatment, but increase in patients with deterioration and recurrence. Continued increase in ferritin levels is associated with a poor prognosis. Therefore, serum ferritin measurement can be particularly useful for patients with alpha-fetoprotein-negative conditions.

Product Specification

Features

Smart - Photosensitive and Luminescent Microspheres

Rapid - Whole Blood Sample Type Supported & No Centrifuge Needed

Convenient - Room Temperature Storage & Minimal sample consumption

Clinical significance

Iron Deficiency Anemia Diagnosis

Monitoring Iron Status

Evaluation of Fatigue and Weakness

Assessment of Hemochromatosis

Guiding Iron Supplementation