Prostate-specific antigen, or PSA, is a protein produced by normal, as well as malignant, cells of the prostate gland. The PSA test measures the level of PSA in a man's blood.
Human pepsinogens I (PGI) and II (PGII) are proenzymes of pepsin—an endoproteinase of gastric juice. PGI is secreted mainly by chief cells in the fundic mucosa, whereas PGII is also secreted by the pyloric glands and the proximal duodenal mucosa. Serum PGI and PGII concentrations and the ratio between PGI and PGII may be related to the histologic and functional status of the gastric mucosa.