Big News Day！Biotime SARS-CoV-2 Antigen Rapid Qualitative Test has been recognized by SFDA. Saudi Food and Drug Authority (SFDA) is an independent body for the Kingdom of Saudi Arabia that aims to ensure food and drug safety for the nation.  The Saudi Ministry of Health has given it responsibility for the regulation of pharmaceuticals, and it is an influential organization among states within the region. Biotime SARS-CoV-2 Antigen Rapid Qualitative Test based on colloidal gold immunochromatography method and intend to use as the qualitative detection of nucleocapsid antigens from SARS-CoV-2 in human nasal swabs, throat swabs, and sputum from individuals who are suspected of COVID-19 by their healthcare provider within the first five days of the onset of symptoms. SFDA authoritative certification means that SARS-CoV-2 Antigen Rapid Qualitative Test is available for sale in Saudi Arabia. If you are interested in this product, please contact us.

On March 10, Biotime donated 2 million of the SARS-COV-2 Antigen Rapid Qualitative Test Kits to Hong Kong. The increasing numbers of the Covid-19 in Hong Kong have been a big concern for the Chinese Government and its people. The Chinese Government has given full support to Hong Kong in its fight against the Covid-19. All sectors of the society and Hong Kong compatriots are helping each other and assisting Hong Kong in its fight against the Covid-19 in various ways. As a company that has long supported global anti-epidemic efforts through In Vitro Diagnostics, Biotime has actively responded to support Hong Kong in its fight against the COVID-19. We donated 12-million-yuan worth of epidemic prevention materials to Hong Kong. Biotime's Vice President of Operations, Jim Huang, presided over the donation ceremony. Mr. Huang said that as POCT developers, especially during the epidemic, we have a greater responsibility to share the worries and difficulties of our country and compatriots. Biotime COVID-19 antigen tests have played an outstanding role in the UK's epidemic prevention and controlling of the spread of Covid-19. Witnessing the Hong Kong epidemic increasing rapidly, Biotime hoped to play a significant role in Hong Kong's anti-epidemic efforts and assist Hong Kong to win the epidemic prevention and control the spread as soon as possible. ▲vice GM of Operation, Jim Huang Afterward, Biotime contacted Yi Zhiming, a member of the Hong Kong Legislative Council. Mr. Yi expressed his gratitude to the Xiamen Municipal Government and Biotime. He stated that the SARS-COV-2 Antigen Rapid Qualitative Test Kits, once they arrived, Covid-19 test kits will be delivered to the citizens quickly so that a protective wall can be built against the epidemic and protect the health of the Hong Kong citizens. Mr. Yi also mentioned working together will bring Hong Kong back to its former glory ▲ Connect with the senator of Legislative Council of the Hong Kong Special Administrative Region Yi Zhiming. ▲ Dong Zhonghong, Office of the Government of the Hong Kong Special Administrative Region in Fujian. Since Biotime was founded, it has committed itself actively to undertakings such as education, disaster relief, and fulfilling its social responsibility as a company and as well as a form of love to the world. As a result of the epidemic, Biotime has displayed "China's strength" in the prevention and control of epidemics across the globe. ▲ Donor Ceremony

More than 18 month since the outbreak, COVID 19 is still raging in much of the world. The novel coronavirus has mutated into strains such as the Delta variant which was first detected in India and accounted for 99% of Covid-19 cases in the UK by mid-Jun, according to Public Health England. (The Guardian, 2021) Delta strain is a highly contagious and possibly more severe SARS-CoV-2 virus strain. Delta is spreading 50% faster than Alpha, which was 50% more contagious than the original strain of SARS-CoV-2—making the new variant 75% more contagious than the original. (YaleMedicine, 2021) And like we’re seeing now, Delta is outcompeting everything else and becoming the dominant strain. The symptoms of the Delta variant appear to differ from traditional COVID symptoms, According to data from the United Kingdom, the most common COVID symptoms may have changed from those we traditionally associated with the virus. Those include: Put aside fever and cough which have always been common COVID symptoms, and headache and sore throat which have traditionally presented for some people, a runny nose is now being reported significantly more frequently. Meanwhile, loss of smell, which was originally quite common, now ranks ninth. (Herrero, 2021) Although it's still not clear whether it it's more dangerous, scientists are becoming more confident the Delta variant represents a more transmissible SARS-CoV-2 strain. (Fox, 2021) What’s even more concerning, is that the Delta variant that has caused devastation in countries like India and the UK has now mutated to produce another variant called Delta Plus. (Joi, 2021) While vaccines are rolling out, not all of us are able to receive them as soon as we'd like. And because not all of us are yet fully protected, get tested if you have any symptoms, even if it’s “just a sniffle”, to protect yourself with some added peace of mind as well as others in your community. Through the course of the pandemic, Biotime’s consolidated its commitment to bringing accessible COVID-19 rapid self-testing to the masses. Hence a wide range of covid 19 test kits has been rolled out and made available both nationwide and worldwide. In particular, the BIOTIME SARS-CoV-2 IgG/IgM Rapid Qualitative Test is a lateral flow immunoassay intended for qualitative detection and differentiation of IgM and IgG antibodies to SARS-CoV-2 in human serum, plasma (potassium EDTA), and potassium EDTA venous whole blood. Our rapid antigen covid test kit is also qualified to detect both asymptomatic and symptomatic COVID-19, helping society collectively return to daily life. In addition to that, some scientific researches have purposefully assessed the use of D-dimer, PCT, CRP, IL-6, Ferritin as biomarkers for disease severity and mortality in COVID-19 patients. And the results are rather convincing to suggest they can provide important information on the prognosis of the novel corona virus infection. Below is Biotime’s product specification. Shop now on our websit...

The International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) has recognized the Biotime BIOT-YG-I Fluorescence Immunoassay Analyzer and the fully-automated HLC-100 High-Performance Liquid Chromatography Analyzer for their safety and qualification to detect glycosylated hemoglobin HbA1c on Big-News Day. As far as glycosylated hemoglobin detection is concerned, the IFCC is the most widely used laboratory standard. As a provider of diabetes screening, diagnosis, blood glucose control and efficacy observation tests, Biotime is dedicated to providing clinicians and patients with accurate and effective test results.

Adlai Nortye Ltd. (“Adlai Nortye”) and Xiamen Biotime Biotechnology Co., Ltd. (“Biotime”) Announce Technical and Commercial Partnership on PD-L1 Inhibitors, Anti-hTNFR2 Antibody Products and Many Other Products Adlai Nortye Biopharma Co., Ltd. a global clinical-stage biopharmaceutical company focused on innovative oncology drugs, with R&D and global clinical operation centers in both China and the United States, has expanded its technical and commercial partnership with Xiamen Biotime Biotechnology Co., Ltd. a Hi-Tech enterprise that specialized in R&D, production, and sales of POCT in vitro diagnostic devices and reagents, and offer the industry’s most comprehensive in vitro diagnostics solutions to more than 60 countries and regions. The agreement aims to boost the development, production and commercialization of the PD-L1 inhibitors AN4005, anti-hTNFR2 antibody products and other products in Greater China and other regions of the world. Under the deal, the total amount of investment has reached several hundreds of millions of yuan which includes the down payment, the milestone payment that triggered by the milestone events and the royalties. The AN4005 Adlai Nortye developed is a drug candidates that made the fastest progress in clinical trials. It shows strong anti-tumour efficacy, good multibinding, high safety and meets clinical and commercial needs，in addition to that, it also shows great potential and might pioneer oral small-molecule inhibitor of PD-L1. AN3025 is a new humanized IgG1anti-hTNFR2 antibody which is in the early part of development of preclinical trial, it’s expected to enhance antitumor immune response which may help to achieved better tumour control and improve treatment. “Indigenous innovation is the core to Biotime, we just create a new business of innovative medicine, increase the research and development funding, take part in the innovative network and try to be a high-quality developer, innovative engineer to the industry.” said Yu Jianping, Executive Secretary of Biotime. “Adlai Nortye is a leading brand of innovative medicine, so this cooperation would be a win-win prospect.” “We are glad to come to an agreement with Biotime who has well-grounded research and technical capabilities, they continue to pursue innovation-driven development and highly value product research. Partnership is expected to begin the process profit-oriented, development of AN4005, AN3025 and other products across the globe. We are confident these products would benefit all the patient in the world and the cooperation would only accelerate the actions we are going to take.” said He Nanhai, Ph.D., Head of Adlai Nortye’s global R&D. About Biotime Established in April 2008, Xiamen Biotime is a Hi-tech enterprise that specialized in R&D, production, and sales of POCT in vitro diagnostic devices and reagents. Biotime has successfully settled the mature medical marketing channels during the past year...

What is NGAL? The full name of NGAL is human lipocalin 2 (Ln2) or siderocalin. It belongs to the lipocalin family and is the earliest proposed marker of acute kidney injury (AKI).   What is the clinical significance of NGAL? 1. NGAL is a marker of acute kidney injury (AKI) When AKI occurs, NGAL rises rapidly in a very short period of time, and the most obvious is 2h. Serum creatinine (sCr), urinary enzymes, etc. often increase significantly after 24 to 72 hours. At this time, the glomerular filtration rate (GFR) has decreased significantly, and NGAL can change before GFR decreases, so it is suitable for early diagnosis of AKI. At the same time, the increase in NGAL concentration is closely related to the duration of AKI, the severity of kidney injury (RIFLE classification), and the treatment effect and prognosis. 2、Can predict the progression of chronic kidney disease (CKD), especially diabetic nephropathy Studies have found that NGAL may be involved in the occurrence and development of diabetes as an inflammatory factor. In diabetic nephropathy, renal tubule damage may be earlier than glomerulus. As a marker of early renal tubular damage, NGAL can reflect renal function damage in diabetic patients (especially type 2 diabetes) before urinary microalbumin (mALB). 3、NGAL also has a certain relationship with tumors Data from different laboratories indicate that the concentration level of NGAL is related to a variety of tumors. It promotes cell proliferation by uptake of iron ions and helps tumor cell growth and infiltration. It is related to tumor cachexia and has become an independent predictor of poor prognosis for patients with cachexia. Compared with traditional projects, what are the advantages of NGAL? When AKI occurs, NGAL rises rapidly in a very short time. The following figure shows the time of increase in the concentration of various markers after the occurrence of AKI: Therefore, testing NGAL can buy more time for AKI patients and grasp the best time for treatment. What are the clinical applications of NGAL? Due to the excellent predictive and diagnostic value of NGAL in AKI, the detection of NGAL can be increased in clinical situations that easily cause AKI. · Routine monitoring after major surgery · Monitoring of ICU patients · Triage of conditions in the emergency department · Early diagnosis of AKI caused by infection and sepsis · Contrast nephropathy (CIN) monitoring after interventional therapy...... NGAL is also an evaluation index of chronic kidney disease, so it can also be used to predict the progression of chronic kidney disease and early detection of kidney damage in patients with diabetic nephropathy. The neutrophil gelatinase-associated lipocalin assay kit provided by Biotime uses fluorescence immunochromatography, which is easy to operate and results in 10 minutes. Product Name：NGAL Rapid Quantitative Test Link: https://www.xiamenbiotime.com/ngal-rapid-quantitative-test_p60.html

Recently, Xiamen Biotime Biotechnology Co., Ltd Monkeypox Virus (MPV) nucleic acid IVD kit (fluorescent PCR method) was certified by the UK MHRA. On July 23, the World Health Organization declared the monkeypox epidemic a "Public Health Emergency of International Concern", which is the highest level of alert issued by the World Health Organization for a global public health emergency, and also means that the current COVID-19 pandemic and the monkeypox epidemic are at this alert level at the same time. Xiamen Biotime Biotechnology Co., Ltd Monkeypox virus nucleic acid test kit adopts rapid PCR amplification mode, and the test kit can obtain the detection result in 40 minutes; it has high specificity and sensitivity, and can detect low concentrations of virus in the sample. There is no cross-reaction between monkeypox virus detection and smallpox virus, vaccinia virus, vaccinia virus, etc. At present, Xiamen Biotime Biotechnology has stockpiled diagnostic technologies such as immunofluorescence, chemiluminescence, molecular diagnosis, electrochemistry, and colloidal gold, contributing "Biotime power" to global public health prevention and control.

This is the official announcement of the National Day of the People's Republic of China. All our customers have been informed that due to the National Day holiday we will be closed on Friday 1st October and will resume normal business on Wednesday 8th October. We salute the founding of our country and the heroic warriors who gave their lives for this country. National Day holiday: October 1 to October 7, 2021 Reopen date: October 8, 2021 During this time, please feel free to call the office if you have any questions about your business. Congratulations and thanks to everyone who has contributed to the success of our business. Xiamen Biotechnology Co., Ltd. 30th September, 2021