The Rippling Effect of Infertility's Pain, Biotime’s Input
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Infertility is when the male or female reproductive system defined by the failure to achieve a pregnancy (conceive) despite having regular unprotected intercourse. Around 1 in 7 couples may have difficulty conceiving. About 84% of couples will conceive naturally within a year if they have regular unprotected intercourse. According to World Health Organization statistics Infertility affects millions of people of reproductive age worldwide – and has an impact on their families and communities. Estimates suggest that between 48 million couples and 186 million individuals live with infertility globally.
Pregnancy is the result of a process that has many steps. To get pregnant:
Is infertility just a woman’s problem?
No, infertility is not always a woman’s problem. Both men and women can contribute to infertility.
What causes infertility in men?
Infertility in men can be caused by different factors and is typically evaluated by a lab test analysis. When a blood analysis is performed, the number of sperm (concentration), motility (movement), and morphology (shape) are assessed by a specialist.
Potential causes of anovulation include the following:
What increases a man’s risk of infertility?
Age - Obese - Smoking - Excessive alcohol and drug use - Exposure to testosterone - Exposure to radiation - Frequent exposure of the testes to high temperatures - Exposure to certain medications - Exposure to environmental toxin.
What causes infertility in women?
A woman’s menstrual cycle is, on average, 28 days long. Day 1 is defined as the first day of “full flow.” Regular predictable periods that occur every 21 to 35 days likely reflect ovulation. A woman with irregular periods is likely not ovulating.
Ovulation can be predicted by using an ovulation predictor kit and can be confirmed by a blood test to check the woman’s progesterone level on day 21 of her menstrual cycle. Although several tests exist to evaluate a woman’s ovarian function, no single test is a perfect predictor of fertility. The most commonly used markers of ovarian function include follicle-stimulating hormone (FSH) value on day 3 to 5 of the menstrual cycle, Luteinizing Hormone (LH), prolactin (PRL) and antral follicle count (AFC) using a transvaginal ultrasound.
Potential causes of anovulation include the following:
Reference:
CDC https://www.cdc.gov/
WHO https://www.who.int/
The National Infertility Association https://resolve.org/
March For Babies https://www.marchofdimes.org/
Mascarenhas MN et al. PLoS Med doi: 10.1371/journal.pmed.1001356
Boivin J, et al. Human reproduction (Oxford, England) doi: 10.1093/humrep/dem046
Rutstein SO, et al. World Health Organization 2004.
Gore AC, et al. Endocrine Reviews doi: 10.1210/er.2015-1010
Segal TR, Fertility and Sterility 2019;112(4):613-21.
Zegers‐Hochschild F, et al., Journal of Gynecology & Obstetrics 2013;123(1):86-89.