May, 2022 — Younger adults with prediabetes mellitus (pDM) have an increased risk for type 1 myocardial infarction (T1MI) hospitalization, according to a study presented at the American Heart Association Quality of Care and Outcomes Research 2022 Scientific Sessions, held from May 13 to 14 in Reston, Virginia.

Rupak Desai, M.B.B.S., from the Atlanta Veterans Affairs Medical Center, and colleagues examined the incidence and odds of T1MI admissions and outcomes using the National Inpatient Sample for 2018 for younger adults (age 18 to 44 years) with and without pDM.

The researchers found that the overall prevalence of pDM was 0.4 percent in younger adults hospitalized in 2018. Among all nondiabetic admission in younger adults, T1MI-related hospitalization (T1RH) was significantly higher in the pDM versus non-pDM cohort (2.15 versus 0.3 percent). T1RH with pDM occurred more often in men, Blacks, Hispanics, Asian/Pacific Islanders, patients from the higher-income quartile, patients from urban-teaching hospitals and Midwest and West region hospitals, and patients with higher rates of hyperlipidemia, obesity, and fluid-electrolyte imbalance. Significantly higher odds of T1MI were seen in the pDM versus non-pDM cohort in univariate and adjusted multivariate analyses. No difference was seen between the cohorts for the T1RH outcome of major cardiovascular and cerebrovascular adverse events.

What Is Prediabetes?

Prediabetes is a serious health condition where blood sugar levels are higher than normal, but not high enough yet to be diagnosed as type 2 diabetes. Using a nationally representative data set comprising 12 years of NHANES data (2005-2016), we estimated the overall prevalence of prediabetes (IFG, IGT, or increased HbA1c level) to be about 1 in 5 for adolescents aged 12 to 18 years and 1 in 4 for young adults aged 19 to 34 years.

What Causes Prediabetes?

Insulin is a hormone made by your pancreas that acts like a key to let blood sugar into cells for use as energy. If you have prediabetes, the cells in your body don’t respond normally to insulin. Your pancreas makes more insulin to try to get cells to respond. Eventually your pancreas can’t keep up, and your blood sugar rises, setting the stage for prediabetes—and type 2 diabetes down the road.

Symptoms

Tests for Type 1 Diabetes, Type 2 Diabetes, and Prediabetes

A1C Test, Fasting Blood Sugar Test, Glucose Tolerance Test, Random Blood Sugar Test.

Solutions

Biotime’s HLC-100 Fully Automated HbA1c Analyzer provides a prompt, reliable solution for diabetes diagnosis. It utilizes the high performance liquid chromatography (HPLC) analytical technique, a gold standard that helps detect glycosylated hemoglobin (HbA1c) with superior precision. Its capability to measure HbA1c, HbF, and other hemoglobin fragments enables clinicians to make quick, accurate diagnoses, thus facilitating timely treatment for the patient.

In pursuit of simplicity, quality assurance, and data security for healthcare organizations, Biotime developed the ALL NEW FLI-100 Immunofluorescence Quantitative Analyser. With the Biotime FLI-100 analyser, you can perform quantitative in vitro assays across a variety of applications, including tests for Type 1 Diabetes, Type 2 Diabetes, and Prediabetes. HbA1c Rapid Quantitative Test is the product of the hemoglobin combining with blood glucose in red blood cells, which can reflect the average blood glucose level over the amid 2-3 months.

Affinity A1c Analyzer is a quantitative detection system based on boronate affinity chromatography, which is used with glycohemoglobin test kit to detect the level of hemoglobin A1c (HbA1c) in human whole blood (venous blood/finger prick). With QC Control Set, Easy-to-use, Handheld size, Room temperature storage, Result in 3 mins and importantly high accuracy & precision (CV≤3.5%)

Reference:

Linda J. Andes et al., JAMA Pediatr. 2020

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